Sarcopenia: An Emerging Giant Greater Than Osteoporosis

Sarcopenia and Osteoporosis

Public health strategies designed to accomodate the ever-increasing human lifespan are urgently required. A good clinical understanding of frailty, as well as knowledge regarding how to prevent it, will therefore be required in order to overcome this challenge. Sarcopenia is an important component of the frailty syndrome, and its association with osteoporosis can lead to fractures and incident ...

COPD: osteoporosis and sarcopenia

Systemic involvement and comorbidities are common in chronic obstructive pulmonary disease (COPD). They add to the burden of disease and are associated with significant disability and mortality. These include cardiovascular disease, mood disorders, anemia, cachexia, skeletal muscle dysfunction and bone pathology. In this article, we review the pathophysiology, diagnosis and treatment of two suc...

Osteoporosis and sarcopenia in older age.

Osteoporosis and sarcopenia are common in older age and associated with significant morbidity and mortality. Consequently, they are both attended by a considerable socioeconomic burden. Osteoporosis was defined by the World Health Organisation (WHO) in 1994 as a bone mineral density of less than 2.5 standard deviations below the sex-specific young adult mean and this characterisation has been a...

Osteoporosis and sarcopenia: two diseases or one?

PURPOSE OF REVIEW This article reviews recently published evidence for common pathways explaining bone and muscle wasting in normal ageing and pathological conditions. RECENT FINDINGS Numerous studies support the concept of a bone-muscle unit, where constant cross-talking between the two tissues takes place, involving molecules released by the skeletal muscle secretome, which affects bone, an...

Osteoporosis and Sarcopenia in Older Adults